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In addition, ACSL4-mediated ferroptosis and lipid metabolism disorders are involved in I/R-induced injuries, AKI, DR, DKD, NASH, NAFLD, and atherosclerosis

Me dochzet k poruchm jejich enzymatickch, strukturnch a vaznch vlastnost, k ovlivnn exprese protein a jejich metabolismu, dysregulaci bunn signalizace a indukci apoptzy i nekrzy