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Description

HIF1: hypoxia-inducible factor1

WellingRBeaumontJJPetersenSJAlexeeff GVSteinmausC

It is increasingly recognized in both cardiovascular and neurodegenerative disorders, where KHcy of proteins such as synuclein and DJ1 drives aggregation and toxicity[17, 18, 56]

WHAT IS OXIDATIVE STRESS

The novel perspective presented herein aims to bridge the current knowledge base to demonstrate the intricate and reinforcing connection between excitotoxicity, oxidative stress, and neuroinflammation while presenting an example of how specific micronutrients may have the unique ability to protect against all three aspects of the neurotoxic triad