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NLRP3 inflammasome activation exacerbates oxidative stress and endothelial dysfunction, while inhibition of the NLRP3 inflammasome signaling pathway can ameliorate vascular dysfunction (184)

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Both p53 and BRCA1-associated protein 1 (BAP1) inhibit the expression of SLC7A11, thereby suppressing the development of RCC by promoting ferroptosis [15, 119, 292, 293]