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Vitamin B12 works with the other B vitamins synergistically to boost energy levels and promote a healthy nervous system and cognitive function

Combining traditional forms of treatment, mainly pharmacotherapy for conditions, with normalization of the intestinal barrier and the state of microbiota can greatly enhance the efficacy and effectiveness of many therapies

Serum methylmalonic acid and holotranscobalamin-II as markers for vitamin B 12 deficiency in end-stage renal disease patients Ann Clin Lab Sci 2013;43:243-9

Numerous studies find that elevated B12 levels are associated with various diseases, including liver and kidney disease