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Earlier framings of these numbers as "intrinsic efficacy multipliers" or "partial agonist" were a measurement-mislabel and are retracted

Cancer Epidemiol Biomarkers Prev 2001;10:385-90

This contrasts with controlled animal model findings, which may not accurately reflect real-world complexities

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Molecular mechanisms of metastasis The genes, which allow transformed cells to invade the surrounding tissue and attract a supportive stroma, can be defined as metastasis initiation genes and could promote cell motility, EMT, extracellular matrix degradation, bone marrow progenitor mobilization, angiogenesis or evasion of the immune system