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Description

PRDX1 stabilizes NFE2L2 by inhibiting cullin 3 (CUL3)-mediated ubiquitination, thereby promoting transcription of genes involved in GSH synthesis ( GCLC , GCLM ) and cystine import ( SLC7A11 ) 113

The Timi Study Group Novartis Pharmaceuticals

Data availability The tumor RNA-seq data generated in this study have been deposited in the SRA database under accession code PRJNA1280553

Christianson, D

10.1016/j.tifs.2020.01.010 Summary Keywords green tea polyphenols (GTPs), aging, antioxidants, D-galactose, inflammatory cytokines, Nrf2 signaling pathway Citation Wang D, Wang T, Li Z, Guo Y and Granato D (2022) Green Tea Polyphenols Upregulate the Nrf2 Signaling Pathway and Suppress Oxidative Stress and Inflammation Markers in D-Galactose-Induced Liver Aging in Mice