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Low vitamin D levels, smoking, obesity, stress, gut microbiota, infections, immunization, heavy metals, and pesticide exposure have been considered risk factors for MS development ( Multiple sclerosis is characterized by a diversified clinical course, generally starting with focal inflammatory events, followed by remissions and relapses

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The TLR-4/NF-B signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss

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Only experimental groups that used exclusively caffeine or isolated xanthines and their respective control groups were included to evaluate the specific effects of these substances on the parameters investigated