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SKU: 7024484232
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Wu et al., 2024)

Small 20 (13), e2308167

[35] A deficiency in these nutrients can slow down gut motility, making the stool harder and leading to constipation

The reduced enzymatic activity increases cellular concentrations of both substrates that NNMT would otherwise consume: S-adenosyl-L-methionine (the universal cellular methyl donor) and nicotinamide (the NAD + salvage precursor)