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The presence of sulfated glycosaminoglycans (GAGs) within the ECM contributes to its swelling pressure (Urban et al., 1985)

Xu Q, Pan J, Yu J, Liu X, Liu L, Zuo X, Wu P, Deng H, Zhang J, Ji A

10.2174/1570159x13666160502153022 124 SikiricP.SeiwerthS.RucmanR.TurkovicB.RokotovD

elegans and ameliorated mutiple aging-related phenotypes, including enhanced resistance to oxidative and thermal stress, improved motility, pharyngeal pumping, defecation rhythm, and reduced lipofuscin/lipid accumulation

What we do know is that maintaining levels above 400 pg/mL ensures optimal red blood cell production critical for oxygen delivery during intense training