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However, very recently, Schubert and colleagues investigated in more detail the function of MCs in arthritis using different strains of MC-deficient mice and in models, either based on autoreactive antibody transfer or effector T cells (57)

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Genetic variation within and between strains of outbred Swiss mice

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While these compounds show promise in preclinical studies, their safety and efficacy in humans remain to be established through proper clinical trials

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Additional information Peer review information Nature Chemistry thanks Junjie Yao, Deju Ye and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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A recently published study has also described a novel differentiation method using Sfrp2 to induce mature cardiomyocytes from human iPSCs [95]

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