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Description

However, very recently, Schubert and colleagues investigated in more detail the function of MCs in arthritis using different strains of MC-deficient mice and in models, either based on autoreactive antibody transfer or effector T cells (57)

Genetic variation within and between strains of outbred Swiss mice

While these compounds show promise in preclinical studies, their safety and efficacy in humans remain to be established through proper clinical trials

Additional information Peer review information Nature Chemistry thanks Junjie Yao, Deju Ye and the other, anonymous, reviewer(s) for their contribution to the peer review of this work