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Poor sleep further impairs emotional regulation, decision-making, and impulse control, increasing vulnerability to relapse during early recovery

Kojic acid and alpha-arbutin are milder alternatives that may take longer to show results but are often gentler on the skin

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For macrophage polarization experiments, cells were then treated with either human recombinant IL-4 (10 ng/mL, Cedarlane Labs, Burlington, ON) or IFN- (10 ng/mL, eBioscience, San Diego, CA) for 48 h

Unlocking the potential of probiotics: a comprehensive review on research, production, and regulation of probiotics