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The integral components of the Bcl-2 family are Bax and Bak, which serve as essential regulators of the intrinsic apoptotic pathway

[7] Riedl E, Pfister F, Braunagel M, Brinkktter P, Sternik P, Deinzer M, Bakker SJ, Henning RH, van den Born J, Krmer BK, Navis G, Hammes HP, Yard B, Koeppel H, Linn T

You can learn more in our guide on how to check for a vitamin deficiency

592,593 Moreover, due to the decrease of 3-hydroxykynurenine (a cytotoxic metabolite of KMO), the mice that lack active kynurenine 3-monooxygenase (KMO) will not develop into AKI after I/R injury

Pavlides S, Tsirigos A, Migneco G, Whitaker-Menezes D, Chiavarina B, Flomenberg N et al