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After conducting the baseline intraoral examinations by two calibrated examiners using a mouth mirror and an explorer, children having teeth with active dentinal caries were invited to participate in the study

Melanotan II (MT-II) is a synthetic analogue of alpha-melanocyte-stimulating hormone (-MSH), a naturally occurring peptide hormone

It may be useful for people with metabolic syndrome

Following the indicated treatment, cells were subjected to a 10-minute incubation with 5 M MitoSOX at 37 C, subsequent to which fluorescence intensity was assessed using a microplate reader (TECAN) at absorption/emission peaks approximately around 396/610 nm