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a) H&E histology, GLS2 IHC, and GS IHC images of liver sections are shown in panels from ODS od/od (GULO mutant) rat treated with 0.2% Ascorbic acid (AsA), ODS od/od rat treated without AsA

115 116 Mechanistically, alcohol-induced CYP2E1 overexpression enhances HBV replication by upregulating hepatocyte nuclear factor-4, the key transcription factor for the HBV core promoter, 117 and increases HCV-related mitochondrial ROS, reducing antioxidant capacity and depleting mitochondrial glutathione, which heightens oxidative damage and cell death

It aids in the formation of DNA and red blood cells that carry oxygen throughout your body

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