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J Tissue Eng Regener Med

Cells were stained with Hoechst 33342 (blue) and LysoTracker DND-26 (green) to visualize the nucleus and lysosomes

Systems pharmacology screening of Phyllanthus fraternus (PF) predicted 51 genes related to drug metabolism or drug transport, including ABCB1, CYP1A1, CYP1A2, CYP2C9, and CYP3A4, suggesting potential HDIs interactions [158]