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monitor patients for the emergence or worsening of depression, suicidal thoughts or behavior, and any unusual changes in moods or behaviors

Jiang, and R

They are two different classes of molecule with two different mechanisms and two different evidence trails, one of which happens to include a body of human physiological data the other simply doesnt have, owing entirely to the fact that one of them is something the body already makes

Two studies using high throughput screening discovered active compounds with IC50 in the nanomolar range [78-79]

If you find the 45 unit mark uncomfortably small to read, the honest options are (a) use a finer-gradation syringe, or (b) follow a protocol built around the 50 mg vial, whose larger draw is more forgiving not to freehand a bigger volume from the 10 mg vial, which would silently overdose relative to the documented figure