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Little is known about the health effects of e-cigarettes, which many users pick up as a less dangerous alternative to smoking, but the nicotine they contain is widely considered harmful to adolescent brain development

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I doubt not, [we] will make and returne such Tobacco this yeere, that even England shall acknowledge the goodnesse thereof. Although Sir Thomas Dale, deputy-governor of Virginia, initially limited tobacco cultivation in the fear that the settlers would neglect basic survival needs in their eagerness to finally get rich, 2,300 pounds of tobacco were exported to the Mother Country in 1615-16

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