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Large-scale, randomized controlled trials are necessary to determine whether coenzyme Q 10 , in conjunction with vitamin E, has therapeutic benefit in FRDA

Horses with minimum activity and maintained on green pasture typically do not need vitamin E supplementation due to adequate natural vitamin E in the fresh grass

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For example, reduced levels of Lactobacillus species were observed in mouse models of cancer cachexia, and Lactobacillus supplementation attenuated muscle wasting in these models, suggesting that Lactobacillus supplementation may serve as a potential therapeutic avenue for cachexia-related muscle atrophy