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We did not detect a change in citric acid cycle component enrichment in the fluids collected during perfusion, suggesting increased tissue metabolic dysregulation rather than excretion into the urine or the buffer (Supplemental Figure 4)

[5, 6] It is considered the main redox buffer in human cells owing to its large amount of reducing equivalents, [7] and is an important enzyme cofactor that serves as a neuromodulator in the central nervous system

Clin Cancer Res

IV Therapy FAQs Oral supplements are processed through the digestive system before entering circulation, and absorption rates vary significantly depending on gut health, formulation, and individual metabolism

8) Selective tumor accumulation