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Children develop characteristic chipmunk facies due to maxillary marrow hyperplasia and frontal bossing

Using this assay to analyze plasma samples from NKTL patient 1, we estimated the amount of circulating Daratumumab in this patient to be 625, 25 and 2.5 ug/ml at 2 weeks (tp0), 7 weeks (tp1) and 13 wpD treatment (tp2) respectively