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(M+D)/2 upregulated TTC5 and HMGCR, involved in p53-dependent apoptosis and cholesterol metabolic process, respectively ( Supplementary Table S1 )

Bhattacharyya et al (234) showed that increased DNMT activity and expression lead to methylation of the DKK3 promoter, which leads to the activation of Wnt/-catenin signalling

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7e), whereas mitochondrial translational (protein synthesis) activity remained unaffected as revealed by mitochondrial protein immunoblotting (Supplementary Fig

& Kolch, W