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CT2 is also involved in the intracellular accumulation of bleomycin in human testicular cancer cells, which are sensitive to this drug (Table 1)

Introduction Cyclic Vomiting Syndrome (CVS) is identified by acute, stereotyped and recurrent episodes of intense nausea with incoercible vomiting, lasting from a few hours to a few days

The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohns disease

It has been shown to have a role to play in enhancing endothelial nitric oxide synthase to produce more NO from L-arginine, which also forms the rationale behind combining the two

Ghoneum M, Agrawal S