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Histamine is stored in "mast cells" on our skin, lungs, and GI tract

Efficient sustained-release nanoparticle delivery system protects nigral neurons in a toxin model of Parkinsons disease

Reduced 5-HT slows intestinal peristalsis by diminishing activation of 5-HT4 receptors in the myenteric plexus

As a result, until recently, it was unclear if white adipocytes received direct synaptic innervation from SNS or if catecholaminergic signalling was perivascular in nature

While many patients are already using peptides, it is important to know that the vast majority of the evidence comes from animal studies, and rigorous human clinical trials are largely absent