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Results Gut microbial metabolism of L -carnitine produces BB as a quantitatively significant product To test whether gut microbial formation of BB might represent a previously unrecognized intermediate in the pro-atherosclerotic effect of dietary L -carnitine and its conversion into TMA and TMAO (Koeth et al., 2013), we first evaluated plasma levels of BB versus TMA, TMAO or carnitine in C57BL/6J, Apoe/ mice placed on either a chemically defined diet (chow) versus the same diet supplemented with L -carnitine (+/ oral antibiotics cocktail to suppress gut microbes)

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doi: 10.1590/S0102-86502008000300009

This is especially true for glutathione