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The vegans averaged 0.76 grams of protein per kilogram of body weight per day (roughly 10% of daily calories from protein), while the Calorie Restriction members averaged 1.73 grams (roughly 24% of calories from protein)

and these naturally occurring defects were studied directly in the brain

This is from the same study you put up Our meta-analysis still has several limitations

J Exp Med 217:20201129

Amplification and cloning of OsD-LDH2 RNA was isolated from rice tissue, reverse transcribed to cDNA which was ultimately used for amplifying the two gene fragments using different primer pairs such that there was an overlap of 109 bp between them