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harbour mutant APP, PS1 and tau) and PDAPP-J20 (expressing Swedish-Indiana APP mutations)

The m6A modification, characterized by the methylation of adenosine at the N6 position in RNA molecules, has emerged as a crucial epitranscriptomic regulator that influences various aspects of RNA metabolism, including splicing, stability, localization, and translation efficiency [11]

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Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

In 1967, MMA was identified as the hallmark of a newly described inborn error of metabolism, methylmalonic aciduria (Oberholzer et al