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Production of ROS is carried out naturally as a result of aerobic metabolism, but it may increase in the presence of certain elements, such as lead (Pb) and cadmium (Cd), which have been reported in breast milk (6)

However, the effect was present only when caloric intake was not strictly controlled

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Together, our data suggest that p53 controls a stress-responsive gene programme, rather than a single downstream gene, that facilitates fasting-dependent recruitment of macrophages into eWAT under metabolic stress