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Reconstituted: Refrigerate at 28 C (35.646.4 F) and use within about 4 weeks

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N Engl J Med 349(5):427434 Felmeden DC et al (2003) Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management

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The activated SIRT2 then deacetylates the key subunit p65 of NF-B, inhibiting its nuclear translocation and thereby effectively blocking NF-B-mediated pro-inflammatory signaling