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Further investigation revealed that both inside and outside of melanoma cells were altered in ways unfavorable for migration and invasion when ENPP2 was reduced by RNAi: cholesterol accumulated inside the melanoma cells, and the ECM was remodeled outside of the cells

Role of exosome-associated microRNA in diagnostic and therapeutic applications to metabolic disorders

Burke A, Smyth EM, Fitzgerald GA

If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Cold plasma reactive species: Generation, properties, and interaction with food biomolecules