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Neuropsychopharmacology 40, 22282239

[DOI] [PubMed] [Google Scholar] 18.Aspden J.L., Eyre-Walker Y.C., Phillips R.J., Amin U., Mumtaz M.A., Brocard M., Couso J.P

6.2 Neural damage mechanisms The molecular disruptions outlined above initiate a series of cascading effects, leading to neural damage through oxidative stress, excitotoxicity, and demyelination

Glutathione helps protect the bodys cells from damage caused by free radicals and oxidative stress

The solved X-ray crystal structure of tetrameric MSA-DH reveals the key catalytic residues Cys 290 and Glu 256 , accessible through opposing substrate and cofactor funnels