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A., Chimitov D

doi: 10.1016/j.bcp.2022.115102 119

We speculate that addressing the challenges described above will elevateTLR-targeted therapies to their full potential and augment the efficacy of immunotherapies for patients

As the RIPK1-targeted inhibitor of necroptosis, necrostatin-1 could both rescue the ferroptosis and necroptosis of RPE cells via inhibiting RIPK1/RIPK3 activation and lipid ROS accumulation (Tong et al., 2023)