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Current therapeutic strategies mitigate these complications by increasing the concentration of RBCs with normal hemoglobin via transfusion, inducing fetal hemoglobin, restoring nitric oxide signaling, inhibiting platelet-endothelium interaction, and stabilizing hemoglobin in its oxygenated state

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Individuals living or training at elevation often show increased CD73 activity, which maintains higher adenosine levels (Boussuges et al., 2022)

In addition, studies have shown that it can also balance the gut microbiome

Acta Reumatol Port 2021;46:7 P1155 Night work and risk of chronic widespread pain among older workers in the UK S