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Compared with normal skin fibroblasts, a greater number of keloid fibroblasts displayed a senescent phenotype and were arrested at the G0/G1 phase using a serum-limited culture approach, indicating the senescent tendency of keloid fibroblasts under simulated ischemic stress

Published 18 July 2014, Vol 13 Issue 5

Dobry Sonia Himed Margo Waters Benjamin H

Regulation of transcription factor NFAT by ADP-ribosylation

The peroxides used in this study were H 2 O 2 and PLPC-OOH, which was prepared by enzymatic hydroperoxidation of 1-palmitoyl-2-linoleoyl-L-3-phosphatidylcholine by lipoxidase as described precisely 30