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Figure 4 The overexpression of vascular endothelial growth factor ( VEGF ) in the RPE and choroid facilitates the penetration of CNV through Bruchs membrane into the subretinal space, thereby promoting the progression of AMD (Thomas et al., 2021)

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Modifications in neurotransmitter levels by modulatory pathways such as the kynurenine pathway, and also changes in accessibility and effects of SCFAs in the brain, may have an impact on BDNF activities such as neural survival and CNS development (70)

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