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The study concludes that CHAC1 is a novel UPR target gene negatively regulated by CHOP, revealing complex regulatory crosstalk in the UPR pathway and providing insights into the molecular mechanisms of oxidative stress and cell death (Nomura et al., 2020)

GSH catabolism supports tumour growth High-throughput screening of cancer cells identified a GGT inhibitor (GGsTop) with increased sensitivity when GSH was provided as a cysteine source

J Pediatr Surg

Agrobacterium-mediated transformation of Amaranthus hypochondriacus : light and tissuespecific expression of a pea chlorophyll a/bbinding protein promoter

While GHK has been shown to inhibit the inflammatory response and epithelial-mesenchymal transition (EMT) via the TGF-1/Smad 2/3 and IGF-1 pathways in bleomycin-induced fibrosis models [24], its broader anti-inflammatory effects in the context of pulmonary fibrosis pathogenesis may warrant further exploration