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12 ] In humans, melatonin production often declines with age, which may contribute to sleep disturbances and disruptions in normal biological timing

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[4] Studies evaluating the effect of peptide exposure in cell cultures have noted that Epithalon appears to directly interact with promoter regions of certain genes such as Tram1, IL-2, CD5, and MMP2 and may also enhance their expression

In further studies, we examined the relationship between FRP targets and these two pathologies (A and tau)