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Prospect Although most of the ADCs currently in clinical practice are based on the modification of natural amino acid sites, due to the difficulty of obtaining a stable DAR ratio at natural amino acid sites, many companies have put their sights into the field of engineering modified amino acid residues with the intention of obtaining A more mean stable ADC

Statin is a commonly prescribed lipid-lowering medication that inhibits HMG-CoA reductase

Clinical application of lentivirus-mediated promotion of TIGAR overexpression still needs to be explored

Authors' contributions BVB: Participated in the literature review and in the writing of this review

Excessive ROS generation can lead to loss of mitochondrial function and apoptosis of lung epithelial cells (Sun et al., 2013)