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504 Inhibiting HDAC5 and HDAC11 can alter adipocyte phenotypes, reducing obesity

Chromatographic separation was then performed at 600nL/min using a 60-min linear gradient that ramped solution B (acetonitrile with 0.1% formic acid) from 3% to 32%

D.SejersenH.Sarker-NagA.AsaraJ

235 WieczfinskaJ.KleniewskaP.PawliczakR

These findings align with the GSEA analysis results mentioned above, where enhanced interferon signaling pathways significantly promoted inflammatory cell infiltration and synovial tissue damage (36, 39, 40)