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Description

M.MuraliA.LandsiedelR

Only when this target and its downstream axis are sufficiently critical can interventions achieve significant anti-obesity and lipid-lowering effects

Liu, H.M

While this might suggest a temporal association between BMAL1 driven transcription/translation of NRF2, we cannot be certain since BMAL1 and CLOCK can each separately bind to other proteins (40, 47) and NRF2 can transcribe genes involved in xenobiotic disposition, protection from electrophiles and general stress response (48, 49)