The applicant searched the FY 2021 MedPAR file to identify eligible cases, with the first analysis using all cases assigned to a list of MS-DRGs to which the technology would most commonly map, the second analysis identifying potential cases using ICD-10-CM diagnosis codes representing patients who may be eligible for the Selux NGP System, and the third analysis combining the results of the first 2 analyses
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Through non-covalent interactions, curcumin (Cur) and poly ()-epigallocatechin-3-gallate (pEGCG) were co-encapsulated within hyaluronic acid (HA) to form HA-CurNPs nanoparticles that exhibited sustained-release properties (Zhang et al., 2018)
Lipid metabolism: the central metabolic process in ferroptosis PUFAs, particularly arachidonic acid (AA)- and adrenic acid (AdA)-enriched phosphatidylethanolamines (PEs), serve as primary substrates for lipid peroxidation initiation, undergoing sequential enzymatic oxidation by long-chain acyl-CoA synthetase 4 (ACSL4), lysophosphatidylcholine acyltransferase 3 (LPCAT3), LOX, and Fe 2+ -mediated Fenton chemistry to generate phospholipid hydroperoxides (PLOOHs) [26]
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