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The accessibility of human skin, which enables characterisation of ageing (den Dekker et al., 2013) and repair (Watson et al., 2009), its susceptibility to molecular damage (Ozols et al., 2021b) and its cellular and extracellular composition, which is similar to other connective tissue-rich organs, make it an excellent system in which to study the action of exogenous peptides in humans

W., Lin, G

Thus, tacrolimus is a topical inhibitor of calcineurin, a protein phosphatase that is essential for the T-cell activation (123)

It involves safely removing the drug from the body under medical supervision

Some improvement in skin radiance is noticed after 23 sessions , with optimal results after a full course