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doi: 10.1038/s41579-020-0433-9 9 ArifuzzamanMCollinsNGuoCJArtisD

Amino acid concentrations were determined using a standard calibration curve prepared with L-leucine

Cerebral pharmacokinetics and microdialysis To confirm that a peptide actually reaches its cerebral target, microdialysis remains the reference tool: Principle : insertion of a semi-permeable membrane probe in a target region (hippocampus, frontal cortex)