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The broad-spectrum antimicrobial activity of PTL, particularly at lower-pH and RONS-rich conditions, could be used for topical application in chronic or recurrent otitis externa , infected wounds, or surgical site infections

EGCG possesses well-documented antioxidant and anti-inflammatory activities but is limited by poor stability and bioavailability [16, 17]

Lund A, Knop FK, Vilsbll T

Although the size increased, the size of the functionalized nanoparticles was still in a range that was deemed suitable for topical application, indicating that the HA functionalization did not affect the desired delivery essentials of the nanoparticles on the skin

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