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Certain factors can influence how the body uses glutathione

In mouse epidermis, topical EPA (10 nmol/cm2, 30 min) protected against UVB-induced immunosuppression, but also increased lipid peroxidation and decreased vitamin C levels compared to oleic acid treated control mice (52)

Wu LY, Kan CN, Cheah IK, Chong JR, Xu X, Vrooman H, et al

Furthermore, previous studies have demonstrated that certain nutritional supplements, such as CLAs at a dosage of 1.2 mg/day for 12 weeks and creatine, can effectively decrease body fat and enhance athletic performance [10, 11]

When combined with proper skincare, hydration, and sun protection, the treatment can contribute to long-term skin wellness and improved skin texture