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Hypoxic preconditioning ameliorates amyloid-beta pathology and longterm cognitive decline in AbetaPP/PS1 transgenic mice

With 126 completed participants (63 per arm), the study is powered at 80% to detect a true difference in the primary outcome measure using a two-tailed analysis with alpha = 0.05, beta = 0.2

Abstract Metformin, a cornerstone therapy for type 2 diabetes mellitus, has emerged as a promising cardioprotective agent with effects that extend well beyond glycemic control