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Description

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

It is known to induce CYP2E1 activity by protein stabilization (18)

Bowman ED, Rothman N, Hackl C, Santella RM, Weston A

Patents and pharmaceutical interest: Washington State University researchers patented Dihexa for potential use in Alzheimers and dementia therapies, but no pharmaceutical company has taken it through regulatory development

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