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Acknowledgements The authors would like to thank every researcher that contributed to the understanding of the close relationship between the IGF-1 deficiency and the Metabolic Syndrome establishment

Thymosin beta-4derived peptides regulate actin filament dynamics, which influences cellular motility, migration of repair-associated cells, and structural remodeling within regenerating tissue [10]

The innate immune response occurs rapidly and can generate effective mechanisms that start rapidly after the infection

Consuming food and beverages containing vitamin B12 is advisable because the body is unable to produce vitamin B12 naturally

French-McCay et al., 2018b