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This approach has allowed us to identify novel DNA adducts, including cross-links in several experimental settings, including tobacco-specific nitrosamine NNK 71 , the gut bacterial-derived genotoxin colibactin 72 , and the chemotherapy agents busulfan and cyclophosphamide 73,74

Li R, Ma T, Gu J, Liang X, Li S

Metabolism of acetaminophen (paracetamol) in plantstwo independent pathways result in the formation of a glutathione and a glucose conjugate

As the excitation wavelength was increased from 330 to 600 nm, the corresponding emission covered almost the entire visible spectrum, as shown in Fig

GSH is critical for growth upon nutrient deprivation and is secreted to support the proliferation of GSH-deficient cells Because GSH is also vital for synthesis of proteins and DNA, we sought to characterize the impact of GSH deficiency in gsh2 mutants on growth under nutrient-depletion, which mimics the nutrient-sequestered host environment