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identified that specific gut microbes inhibit remodeling-associated cytokines (IL-4, IL-5, IL-9, IL-13) through SCFA production, mitigating airway wall thickening ( Lactobacillus rhamnosus (Lr) administration reduced leukocyte infiltration, bronchial hyperreactivity, and remodeling markers (IL-4, IL-5, IL-13, STAT6, GATA3, IL-17, IL-21, IL-22, STAT3, RORt) in asthma-COPD overlap syndrome (Vasconcelos et al., 2023)

Certain painkillers (NSAIDs), antibiotics like tetracyclines, antimalarial drugs, some chemotherapy drugs, and even some heavy metals are common causes of dark lips induced by medications 2

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This high-potency dose supports cellular defence against oxidative stress, promotes healthy liver detox pathways, and helps maintain respiratory and immune function.*

However, its effects on homeostasis are complex and highly dependent on the type, intensity, duration, and recovery status of the exercise [22, 23]