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The reduction of glutathione peroxidase 4 (GPX4), an enzyme that lowers lipid hydroperoxides and inhibits lipid peroxidation, is one important mechanism (67)

doi: 10.3389/fcimb.2021.745016 Summary Keywords tetrahydrobiopterin, radiotherapy, nitric oxide synthase, immunotherapy, immunometabolism, vascular normalization, cancer, S-nitrosylation Citation Clark GC, Lai A, Agarwal A, Liu Z and Wang X-Y (2024) Biopterin metabolism and nitric oxide recoupling in cancer

Cell Mol Life Sci 79(1):6 Li J, Li X, Song S et al (2023) Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases

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